Radix Ginseng


The Effect of Polysaccharides of Some Chinese Herbs on Mice Natural Killer (NK) Cell Activity
Fang Xunxin Liang Minrou Wang Jianhua. Pharmacology and Clinics of Chinese Materia Medica 1990-01  
After 3-h culture with polysaccharide of Radix Ginseng at 37C in a CO2-inculatoi, mice NK cells could get more active (P0.01). Dose response studies showed that polysaccharide of Radix Ginseng could enhance, at concentration ranged from 30ug/ml to 120ug/ml,mice NK cell activity assayed against YAC-1 target cells. At a concentration of 100/ug/ml, CMPM Oould enhance the NK cell activity, polysaccharide-k has no effect on mice NK cell activity by the same method when its dose ranged from 50-40ug/ml, The NK cell cytotoxicity of "Spleen deficient" mouse was significantly decreased to 3.52+.35 from 7.98+0.87(X+SD) ,P0.01. When cultured with 500ug/ml Radix Ginseng polysaccharide at 37C in a CO2-incubator for 3-h, the inhibited NK cell cytotoxicity increased to 6.45+0.99, from 3.52+1.35.It cought be suggested that NK cell activity might be one of the forms of "Spleen" in Traditional Chinese pedicine

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